Dietary adaptation of FADS genes in Europe varied across time and geography

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Dietary adaptation of FADS genes in Europe varied across time and geography

Fatty acid desaturase (FADS) genes encode rate-limiting enzymes for the biosynthesis of omega-6 and omega-3 long-chain polyunsaturated fatty acids (LCPUFAs). This biosynthesis is essential for individuals subsisting on LCPUFA-poor diets (for example, plant-based). Positive selection on FADS genes has been reported in multiple populations, but its cause and pattern in Europeans remain unknown. H...

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ژورنال

عنوان ژورنال: Nature Ecology & Evolution

سال: 2017

ISSN: 2397-334X

DOI: 10.1038/s41559-017-0167